Standards; Isotopic Labeled Analogues; Environmental Standards, Mutagens and Metabolites; Nicotine Derivatives and Metabolites;
應(yīng)用:
(RS)-Nornicotine-13C6 is an isotope labelled analog of (RS)-Nornicotine (N757000), a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity.
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