產品基本信息
產品編號：T789510
產品名稱：N-Trifluoroacetyl-N-methyl-deacetylcolchicine
產品CAS：71295-35-7
規(guī)格含量：2.5g
產品價格：面議
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產品詳細介紹
標準品編號:
T789510
名稱:
N-Trifluoroacetyl-N-methyl-deacetylcolchicine
別名:
(S)-2,2,2-Trifluoro-N-methyl-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; N-(Trifluoroacetyl)demecolchine; N-Trifluoroacetyldemecolcine; NSC 317022;
CAS號:
71295-35-7
分子式:
C??H??F?NO?
外觀:
Yellow Solid
分子量:
467.43
溶解度:
Chloromethane, Dichlormethane, DMSO, Methanol
類別:
Standards; Enzyme Activators and Inhibitors;
應用:
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
參考文獻
Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),
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