tert-?Butyl 4-?(4,?4,?5,?5-?tetramethyl-?1,?3,?2-?dioxaborolan-?2-?yl)?-?2,?3,?6,?7-?tetrahydro-?1H-?azepine-?1-?carboxylate is a reagent used in the preparation of heteroarylcarboxamides and arylcarboxamides as inhibitors of WDR5 protein-protein binding.