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產(chǎn)品基本信息

產(chǎn)品編號：Q700550

產(chǎn)品名稱：2,3-Quinolinedimethanol

產(chǎn)品CAS：57032-14-1

規(guī)格含量：1g

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	Q700550
名稱:	2,3-Quinolinedimethanol
別名:	Quinoline-2,3-diyldimethanol
CAS號:	57032-14-1
分子式:	C??H??NO?
分子量:	189.21
類別:	Building Blocks; Miscellaneous;
應(yīng)用:	2,3-Quinolinedimethanol is a reactant used in the synthesis of camptothecin (C175150), an ntitumor alkaloid which binds irreversible to the DNVIP(LA)topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent
參考文獻	Xu, P., et. al.: Chem-Asian J., 10, 976 (2015)Potmesil, M., et al.: Cancer Res., 54, 1431 (1994); Desai, S.D., et al.: J. Biol. Chem., 272, 24159 (1997); Fan, Y., et al.: J. Med. Chem., 41, 2216 (1998); Kaufmann, S.H., et al.: Biochim. Biophys. Acta, 1400, 195 (1998)

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