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產(chǎn)品基本信息

產(chǎn)品編號(hào)：R700930

產(chǎn)品名稱：RS-127445 Hydrochloride

產(chǎn)品CAS：199864-86-3

規(guī)格含量：100mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	R700930
名稱:	RS-127445 Hydrochloride
別名:	4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine Hydrochloride; 2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine Monohydrochloride; MT 500 Hydrochloride;
CAS號(hào):	199864-86-3
參考CAS號(hào):	Free Base: 199864-87-4
分子式:	C??H??ClFN?
分子量:	317.79
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.
參考文獻(xiàn)	Mokrosz, J., et al.: Pharmazie, 49, 801 (1994), Hoyer., et al.: Pharmacol. Rev., 46, 157 (1994), Martin., et al.: Neuropharmacol., 33, 261 (1994),

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