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產(chǎn)品基本信息

產(chǎn)品編號：C270500

產(chǎn)品名稱：Cercosporamide

產(chǎn)品CAS：131436-22-1

規(guī)格含量：500Âµg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	C270500
名稱:	Cercosporamide
別名:	(9aS)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancarboxamide;(S)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancarboxamide; (-)-Cercosporamide;
CAS號:	131436-22-1
分子式:	C??H??NO?
分子量:	331.28
類別:	Research Tools;
應用:	Cercosporamide is a potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3. Cercosporamide effectively inhibits eIF4E phosphorylation as well as inibitiing inhibits Pkc1. Cercosporamide displays antiproliferative and proapoptotic activity in cancer cells in vitro.
參考文獻	Sussman, A. et al.: Eukaryot. Cell, 3, 932 (2004); Konicek, B.W. et al.: Cancer Res., 71, 1849 (2011); Hou, J. et al.: Oncotarget, 3, 118 (2012);

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