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產(chǎn)品基本信息

產(chǎn)品編號：D450132

產(chǎn)品名稱：11-ent-Mifepristone-5-chloro-3,2’-[1,3]dioxolane

產(chǎn)品CAS：

規(guī)格含量：2.5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	D450132
名稱:	11-ent-Mifepristone-5-chloro-3,2’-[1,3]dioxolane
別名:	(5S,8S,11S,13S,14S,17S)-11-(4-(Dimethylamino)phenyl)-13-methyl-17-(prop-1-yn-1-yl)-1,2,4,5,6,7,8,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-5,17-diol; Estra-5(10),9(11)-diene-3,17-dione11-(4-(dimethylamino)phenyl)-17-(prop-1-yn-1-yl) 3-Ethylene Ketal
分子式:	C??H??NO?
外觀:	Off-white solid
分子量:	491.66
溶解性:	Dichloromethane; Ethyl Acetate; Methanol
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	11-ent-Mifepristone-5-chloro-3,2’-[1,3]dioxolane is an intermediate in the synthesis of 11-ent-Mifepristone (M343980), which is an enantiomic impurity of Mifepristone (M343975), a progesterone receptor antagonist with partial agonist activity.
參考文獻(xiàn)	Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)

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