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產(chǎn)品基本信息

產(chǎn)品編號：G800510

產(chǎn)品名稱：GT 949

產(chǎn)品CAS：460330-27-2

規(guī)格含量：2.5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	G800510
名稱:	GT 949
別名:	3-((4-Cyclohexylpiperazin-1-yl)(1-phenethyl-1H-tetrazol-5-yl)methyl)-6-methoxyquinolin-2(1H)-one
CAS號:	460330-27-2
分子式:	C??H??N?O?
分子量:	527.66
種類:	Standards; Enzyme Activators and Inhibitors;
應(yīng)用:	GT 949 is a selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM). Enhances the glutamate translocation rate, with no effect on substrate interaction. Increases glutamate removal by 70%. Exhibits no effect on DAT, SERT and NET or NMDA receptors.
參考文獻	Kortagere, Sandhya., et al.: ACS Chem Neurosci., 9,522 (2018)

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