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產(chǎn)品基本信息

產(chǎn)品編號：M288620

產(chǎn)品名稱：rel-(1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-yl aceta

產(chǎn)品CAS：136310-66-2

規(guī)格含量：2mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	M288620
名稱:	rel-(1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-yl acetate
別名:	endo-α-Hydroxy-α-2-thienyl-8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-y Ester 2-Thiopheneacetic Acid; Di(2-thienyl)glycolic Acid Tropenol Ester
雜質(zhì):	Tiotropium EP impurity D
CAS號:	136310-66-2
分子式:	C??H??NO?S?
外觀:	Light Beige to Light Brown Solid
熔點:	>134°C (dec.)
分子量:	361.48
儲存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly, Heated), Methanol (Slightly)
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	(1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-ylacetate is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.
參考文獻	Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);

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