Hygroscopic, -20°C Freezer, Under Inert Atmosphere
溶解度:
Acetone (Slightly), Methanol (Slightly, Heated)
類別:
Standards; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
應(yīng)用:
Patulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation of glutathione in Hep G2 cells. Patulin is an antibiotic. Patulin-induced nephropathy and gastrointestinal tract malfunction have been demonstrated in several animal models. The oral LD50 value of patulin ranges between 29 and 55 mg/kg body weight in rodents and 170 mg/kg body weight in poultry. The World Health Organization considers patulin cytotoxic and established a safety level of patulin in apple juice at 50 μM. At 100-200 μM, patulin can directly increase intracellular oxidative stress in HEK293 and HL-60 cells. In 1944, this compound was tested in a clinical trial for potential antibioti
危險(xiǎn)品:
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
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