Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
PHVIP(LA)793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHVIP(LA)793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHVIP(LA)793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.
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