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產(chǎn)品基本信息

產(chǎn)品編號(hào)：C366123

產(chǎn)品名稱(chēng)：7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one

產(chǎn)品CAS：137982-91-3

規(guī)格含量：100mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	C366123
名稱(chēng):	7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
別名:	1-(2-Methyl-4-nitrobenzoyl)-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one; 7-Chloro-1-(2-methyl-4-nitrobenzoyl)-5-oxo-2,3,4,5+tetrahydro-1H-1-benzazepine;7-Chloro-1-(2-methyl-4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
CAS號(hào):	137982-91-3
分子式:	C??H??ClN?O?
外觀:	Off-white Solid
分子量:	358.78
類(lèi)別:	Standards; Benzodiazepines;
應(yīng)用:	7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is an intermediate in synthesizing Tolvaptan-d7 (T536652), a labelled Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
參考文獻(xiàn)	Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006)

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