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產(chǎn)品基本信息

產(chǎn)品編號(hào)：H825760

產(chǎn)品名稱：25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt

產(chǎn)品CAS：1174047-40-5

規(guī)格含量：5mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	H825760
名稱:	25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt
別名:	Sodium (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl Sulfate
CAS號(hào):	1174047-40-5
參考CAS號(hào):	884905-07-1 free acid
分子式:	C??H??NaO?S
分子量:	504.7
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
應(yīng)用:	25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
參考文獻(xiàn)	Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),

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