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產(chǎn)品基本信息

產(chǎn)品編號：H917982

產(chǎn)品名稱：4β-Hydroxy Cholesterol-d7

產(chǎn)品CAS：1246302-80-6

規(guī)格含量：10mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	H917982
名稱:	4β-Hydroxy Cholesterol-d7
別名:	(3β,4β)-Cholest-5-ene-3,4-diol-d7; Cholest-5-ene-3β,4β-diol-d7; 3β,4β-Dihydroxycholest-5-ene-d7; cis-3,4-Dihydroxy-5-cholestene-d7; cis-5-Cholestene-3,4-diol-d7;
CAS號:	1246302-80-6
參考CAS號:	17320-10-4 (unlabelled)
分子式:	C??H??D?O?
外觀:	白色至白色固體
熔點:	154-159°C
分子量:	409.7
儲存:	冰箱
溶解度:	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
種類:	Standards; Steroids; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
參考文獻(xiàn)	Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),

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