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產(chǎn)品基本信息

產(chǎn)品編號：J211310

產(chǎn)品名稱：JNJ-7706621

產(chǎn)品CAS：443797-96-4

規(guī)格含量：5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	J211310
名稱:	JNJ-7706621
別名:	N3-[4-(Aminosulfonyl)phenyl]-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazole-3,5-diamine; 4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-yl]amino]benzenesulfonamide; JNJ 770662;
CAS號:	443797-96-4
分子式:	C??H??F?N?O?S
分子量:	394.36
種類:	Research Tools;
應(yīng)用:	JNJ-770662 is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. JNJ-770662 has been shown to induce growth suppression and mitotic defects, these results suggest that JNJ-7706621 could be useful for cell cycle analysis and therapy of various cancers, including Ewing's sarcoma.
參考文獻(xiàn)	Matsuhashi, A. et al.: Curr. Cancer Drug Tar., 12, 625 (2012); Emanue,l S. et al.: Cancer Res., 65, 9038 (2005); Seamon, J.A. et al.: Mol. Cancer Ther., 5, 2459 (2006);

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