Picropodophyllin-d3; AXL 1717-d3; NSC 36407-d3; [5R-(5α,5aα,8aα,9α)]-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxy-d3-phenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; (5R,5aS,8aR,9R)-9-Hydroxy-5-(3,4,5-trimethoxy-d3-phenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one
CAS號:
1454782-81-0
參考CAS號:
Unlabelled: 477-47-4
分子式:
C??H??D?O?
外觀:
白色固體
熔點:
201-207°C
分子量:
417.42
儲存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
Chloroform (Slightly)
類別:
Building Blocks; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應用:
Picropodophyllotoxin-d3 is the labeled analogue of Picropodophyllotoxin (P437620), an insulin-like growth factor 1 receptor (IGF-1R) inhibitor that selectively inhibits the growth of human hepatocellular cancer cells with no observed cytotoxicity on normal cells.
危險品:
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package