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產(chǎn)品基本信息

產(chǎn)品編號(hào)：R143325

產(chǎn)品名稱：Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide

產(chǎn)品CAS：

規(guī)格含量：10mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	R143325
名稱:	Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide
別名:	4-(4-(3-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)-3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(methylcarbamoyl)pyridine 1-Oxide
分子式:	C??H??ClF?N?O??
分子量:	674.94
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.
參考文獻(xiàn)	Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)

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