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產(chǎn)品基本信息

產(chǎn)品編號：A601665

產(chǎn)品名稱：N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-M

產(chǎn)品CAS：376633-26-0

規(guī)格含量：50mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標(biāo)準(zhǔn)品編號:	A601665
名稱:	N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester
別名:	GS 7485;
CAS號:	376633-26-0
分子式:	C??H??N?O?P
分子量:	400.37
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester prorug of PMPA, phenyl monophosphoramidate, and is a Tenofovir (T018500) derivative, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
參考:	Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007), Lee, W. et al.: Antimicrob. Agents Chemother., 49, 1898 (2005);

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