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產品基本信息

產品編號：D474975

產品名稱：Dimethyl 2-Methyl-4-phenyl-6-(4-((triphenylphosphoranylidene)amino)butyl)-1,4-dihydropyrid

產品CAS：

規(guī)格含量：50mg

產品價格：面議

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產品詳細介紹

標準品編號:	D474975
名稱:	Dimethyl 2-Methyl-4-phenyl-6-(4-((triphenylphosphoranylidene)amino)butyl)-1,4-dihydropyridine-3,5-dicarboxylate
分子式:	C??H??N?O?P
分子量:	618.7
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用:	Dimethyl 2-Methyl-4-phenyl-6-(4-((triphenylphosphoranylidene)amino)butyl)-1,4-dihydropyridine-3,5-dicarboxylate is an intermediate used in the synthesis of Amlodipine Dimethyl Ester (A633560), a Amlodipine Besilate (A633560) impurity, which is a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive.
參考文獻	Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007); Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996);

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