Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
6-Fluoro-3,4-dihydro-3-oxo-4-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2-pyrazinecarboxamide is an intermediate in synthesizing T-705RTP (T003210), a derivative of T-705 (F103350) which has activity against the lethal H5N1 influenza A viruses. T-705RTP which has the triphosphate group, gets strongly inhibited by the influenza virus RNA polymerase activity in comparison with T-705RMP (T003202).
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