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產(chǎn)品基本信息

產(chǎn)品編號：N519947

產(chǎn)品名稱：4-?(6-?Nitro-?3-?pyridinyl)?-1-?piperazine-?2,?2,?6,?6-?d4-?carboxy

產(chǎn)品CAS：2089333-15-1

規(guī)格含量：50mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	N519947
名稱:	4-?(6-?Nitro-?3-?pyridinyl)?-1-?piperazine-?2,?2,?6,?6-?d4-?carboxylic Acid 1,?1-?Dimethylethyl Ester
別名:	4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic Acid-d4 1,1-Dimethylethyl Ester; 4-(6-Nitropyridin-3-yl)piperazine-1-carboxylic-d4 Acid t-Butyl Ester;t-Butyl 4-(6-Nitro-3-pyridyl)piperazine-1-carboxylate-d4;t-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-carboxylate-d4
CAS號:	2089333-15-1
參考CAS號:	類似: 571189-16-7
分子式:	C??H??D?N?O?
外觀:	Yellow Solid
分子量:	312.36
溶解度:	Dichloromethane; Ethyl Acetate; Methanol
種類:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	4-?(6-?Nitro-?3-?pyridinyl)?-1-?piperazine-?2,?2,?6,?6-?d4-?carboxylic Acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing Palbociclib-d4 (P139901), an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
參考文獻(xiàn)	Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)

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