對照品 > 標準品 > 美國藥典 >
產(chǎn)品基本信息
產(chǎn)品編號：M425460
產(chǎn)品名稱：MM-419447 (Linaclotide Metabolite) Trifluoroacetic acid
產(chǎn)品CAS：
規(guī)格含量：2.5mg
產(chǎn)品價格：面議
聯(lián)系我們:
產(chǎn)品詳細介紹
標準品編號:
M425460
名稱:
MM-419447 (Linaclotide Metabolite) Trifluoroacetic acid
別名:
L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteine trifluoroacetic acid; 132: PN: US20050020811 SEQID: 125 Claimed Sequence; 13: PN: WO2014151200 SEQID: 56 Claimed Protein; 44: PN: US20120237593 SEQID: 56 Claimed Sequence; 5: PN: WO2016015055 SEQID: 6 Claimed Sequence; 652: PN: WO2007022531 PAGE: 248 Claimed Protein; 65: PN: WO2005087797 SEQID: 71 Unclaimed Sequence; 78: PN: US20090062207 SEQID: 81 Unclaimed Protein; 80: PN: US20060281682 SEQID: 81 Claimed Protein; 81: PN: US20060258593 SEQID: 81 Unclaimed Protein; 90: PN: WO2008106429 PAGE: 4/64 Unclaimed Protein; 9: PN: WO2010027405 SEQID: 9 Claimed Protein;
參考CAS號:
832118-08-8
分子式:
C??H??N??O??S? • x(C ?HF?O?)
外觀:
白色固體
熔點:
>261°C (dec.)
分子量:
1369.61114
儲存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
種類:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用:
MM-419447 is a Linaclotide metabolite, which is a guanylate cyclase-C agonist currently being studied in Phase 3 trials for the treatment of irritable bowel syndrome with constipation.
參考文獻
Chey, W.D., et al.: Am. J. Gastroenterol., 107, 1702 (2012); Rao, S., et al.: Am. J. Gastroentrol., 107, 1714 (2012); Brierley, S.M., et al.: Curr. Opinion. Pharmacol., 12, 632 (2012);
?您的位置：
