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產(chǎn)品基本信息

產(chǎn)品編號(hào)：D299050

產(chǎn)品名稱：Dexrazoxane

產(chǎn)品CAS：24584-09-6

規(guī)格含量：50mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	D299050
名稱:	Dexrazoxane
別名:	4,4'-[(1S)-1-Methyl-1,2-ethanediyl]bis-2,6-piperazinedione; (S)-4,4'-(1-Methyl-1,2-ethanediyl)bis-2,6-piperazinedione; (+)-4,4'-Propylenedi-2,6-piperazinedione; (+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; (S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; ADR 529; ICRF 187; NSC 169780; Savene; Totect; Zinecard
CAS號(hào):	24584-09-6
分子式:	C??H??N?O?
外觀:	白色至Pale Yellow solid
熔點(diǎn):	>186°C (dec.)
分子量:	268.27
儲(chǔ)存:	冰箱保存
溶解性:	DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Dexrazoxane is a cardioprotective compound against anthracyclines. It is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.
參考文獻(xiàn)	Walker, D., et al.: Pediatr. Blood Cancer 60,616 (2013); Kang, M., et al.: J. Chemother., 24, 292 (2012); Lipshultz, S., et al.: New England J. Med., 35, 145 (2004)

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