產(chǎn)品基本信息
產(chǎn)品編號：F595670
產(chǎn)品名稱：(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
產(chǎn)品CAS：93957-50-7
規(guī)格含量：2g
產(chǎn)品價格：面議
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產(chǎn)品詳細介紹
標(biāo)準(zhǔn)品編號:
F595670
名稱:
(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
別名:
(E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal; (2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal; (E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein
CAS號:
93957-50-7
分子式:
C??H??FNO
外觀:
Yellow Solid
熔點:
>132°C (dec.)
分子量:
307.36
儲存:
冰箱保存, under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
種類:
Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde is an intermediate in the synthesis of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
參考文獻
Sacharia, J.R., et. al.: J. Org. Chem., 75, 7514 (2010); Kim, A., Kim, I.S.: Bull. Korean Chem. Soc., 32, 3748 (2011); Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)
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