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產(chǎn)品基本信息

產(chǎn)品編號(hào)：H949698

產(chǎn)品名稱：rac-N-?[(1R)?-?2-?Hydroxy-?3-?methyl-?1-?(2-?methylpropyl)?-?3-?but

產(chǎn)品CAS：

規(guī)格含量：25mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	H949698
名稱:	rac-N-?[(1R)?-?2-?Hydroxy-?3-?methyl-?1-?(2-?methylpropyl)?-?3-?buten-?1-?yl]?-?carbamic Acid 1,?1-?Dimethylethyl Ester
別名:	rac-t-Butyl ((4R)-3-Hydroxy-2,6-dimethylhept-1-en-4-yl)carbamate
分子式:	C??H??NO?
外觀:	Solid
分子量:	257.37
種類:	Standards; Chiral Molecules;
應(yīng)用:	rac-N-?[(1R)?-?2-?Hydroxy-?3-?methyl-?1-?(2-?methylpropyl)?-?3-?buten-?1-?yl]?-?carbamic Acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing (R)-2-Amino-4-methyl-1-((S)-2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt (A605100), an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
參考文獻(xiàn)	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012)

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