8-Chloro-6,11-dihydro-11-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Impurity B; Desloratadine EP Impurity B
雜質(zhì):
Desloratadine EP Impurity B
CAS號(hào):
183198-49-4
分子式:
C??H??ClN?
外觀:
白色至Red Solid
熔點(diǎn):
>65°C (dec.)
分子量:
310.82
儲(chǔ)存:
Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
穩(wěn)定性:
Hygroscopic
種類:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Iso Desloratadine (Desloratadine EP Impurity B) is an impurity of Desloratadine (D290250), which is a nonsedating-type histamine H1-receptor antagonist. Desloratadine is an active metabolite of Loratadine (L469575). Also inhibits generation and release of inflammatory mediators from basophils and mast cells. An impurity arising in the synthesis of Rupatadine (R701650).
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