4-?(4-Methyl-?1-?piperazinyl)?-?6-?(1H-?pyrazol-?4-?yl)?quinazoline is a useful compound in preparation of (N-containing heterocyclyl(pyrazole as inhibitors of activation of STAT6 protein and/or IL-4 and/or IL-13 signal transduction as preventives and/or remedies of diseases.