產(chǎn)品基本信息
產(chǎn)品編號(hào):M755443
產(chǎn)品名稱:MS023
產(chǎn)品CAS:1831110-54-3
規(guī)格含量:5mg
產(chǎn)品價(jià)格:面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
M755443
名稱:
MS023
別名:
N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine
CAS號(hào):
1831110-54-3
分子式:
C??H??N?O
分子量:
287.4
種類:
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues.
參考文獻(xiàn)
Eram, Mohammad S., et al.: ACS Chemical Biology,11,772-(2016); Ferreira de Freitas, Renato., et al.: J. Med. Chem., 59,6838 (2016)