trans-2-Pentenoic Acid Chloride is an intermediate useful in the synthesis of (1S,2R)-Tapentadol Hydrochloride (T007225), which is the (1S,2R)-isomer of Tapentadol (T007200, HCl); a novel, centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical and clinical models of pain relief.
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