產(chǎn)品基本信息
產(chǎn)品編號(hào)：R637310
產(chǎn)品名稱：Ro3280
產(chǎn)品CAS：1062243-51-9
規(guī)格含量：5mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
R637310
名稱:
Ro3280
別名:
4-((9-Cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide; 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide
CAS號(hào):
1062243-51-9
分子式:
C??H??F?N?O?
分子量:
543.61
類別:
Research Tools;
應(yīng)用:
Ro3280 is a Polo-like kinase 1 (PLK1) inhibitor. Ro3280 shows strong antitumor activity in xenograft mouse models, has good selectivity against other kinases and has excellent in vitro cellular potency.
參考文獻(xiàn)
Chen, S., et. al.: Bioorg. Med. Chem. Lett., 22, 1247 (2012);
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