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產(chǎn)品基本信息

產(chǎn)品編號(hào)：T345135

產(chǎn)品名稱(chēng)：1,3-Thiazol-5-ylmethyl N-[(1S)-1-((4S,6S)-4-Benzyl-2-oxo-1,3-oxazinan-6-yl)-2-phenylethyl]

產(chǎn)品CAS：1010809-52-5

規(guī)格含量：100mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	T345135
名稱(chēng):	1,3-Thiazol-5-ylmethyl N-[(1S)-1-((4S,6S)-4-Benzyl-2-oxo-1,3-oxazinan-6-yl)-2-phenylethyl]carbamate
別名:	N-?[(1S)?-?2-?Phenyl-?1-?[(4S,?6S)?-?tetrahydro-?2-?oxo-?4-?(phenylmethyl)?-?2H-?1,?3-?oxazin-?6-?yl]?ethyl]?-?Carbamic Acid 5-?Thiazolylmethyl Ester
CAS號(hào):	1010809-52-5
分子式:	C??H??N?O?S
外觀:	Yellow Solid
分子量:	451.54
溶解度:	Dichloromethane;
類(lèi)別:	Building Blocks; Chiral Molecules;
應(yīng)用:	1,3-Thiazol-5-ylmethyl N-[(1S)-1-((4S,6S)-4-Benzyl-2-oxo-1,3-oxazinan-6-yl)-2-phenylethyl]carbamate is an intermediate in synthesizing Bis(thiazol-5-yl-methyl)[carbonylbis[imino[(2S,3S,5S)-3-hydroxy-1,6-diphenylhexane-5,2-diyl]]]dicarbamate (R535035). Ritonavir Impurity P is derived from 2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane (A630525), which is an intermediate in the synthesis of Ritonavir (R535000), a selective HIV protease inhibitor.w
參考文獻(xiàn)	Kempf, D., et al.: J. Med. Chem., 41, 602 (1998); Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994); Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003); Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005); Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788(2006)

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