Hygroscopic, -20ËšC Freezer, Under Inert Atmosphere
溶解性:
DMSO (Slightly), Methanol (Slightly, Heated)
穩(wěn)定性:
Unstable in solution
種類:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt is a major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers).