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N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel

產(chǎn)品基本信息

產(chǎn)品編號：D204050

產(chǎn)品名稱：N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel

產(chǎn)品CAS：502626-06-4

規(guī)格含量：2.5mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	D204050
名稱:	N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel
別名:	(αR,βS)-α-Hydroxy-β-[[(2E)-1-oxo-2-hexen-1-yl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; (αR,βS)-α-Hydroxy-β-[[(2E)-1-oxo-2-hexenyl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; Paclitaxel Impurity Q; Paclitaxel - Impurity Q
雜質(zhì):	Paclitaxel - Impurity Q
CAS號:	502626-06-4
分子式:	C??H??NO??
外觀:	白色固體
熔點:	161-167°C
分子量:	845.93
儲存:	-20Â°C Freezer
溶解性:	Chloroform (Slightly), Methanol (Slightly)
種類:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel is an impurity of Paclitaxel (P132500); an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Paclitaxel - Impurity Q.
參考文獻(xiàn)	Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984); Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984); Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995); Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002); Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004)

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