產(chǎn)品基本信息
產(chǎn)品編號：D445698
產(chǎn)品名稱：4,4-Difluorocyclohexanecarboxylic Acid Ethyl Ester
產(chǎn)品CAS：178312-47-5
規(guī)格含量：5g
產(chǎn)品價格：面議
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產(chǎn)品詳細介紹
標準品編號:
D445698
名稱:
4,4-Difluorocyclohexanecarboxylic Acid Ethyl Ester
別名:
Ethyl 4,4-Difluorocyclohexanecarboxylate;
CAS號:
178312-47-5
分子式:
C?H??F?O?
分子量:
192.2
種類:
Building Blocks; Miscellaneous;
應(yīng)用:
4,4-Difluorocyclohexanecarboxylic Acid Ethyl Ester is used as a reactant in the preparation of antiretroviral drug Maraviroc (M193000), which is CCR-5 receptor antagonist used for the treatment of HIV.
參考文獻
Fumero, E., et al.: Clin. Microbiol. Infect., 9, 1077 (2003); Walker, D.K., et al.: Drug Metab. Dispos., 33, 587 (2005); Wood, A., et al.: Prog. Med. Chem., 43, 239 (2005); Haycock-Lewandowski, S., et al.: Org. Process Res. Dev., 12, 1094 (2008);
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