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| 產(chǎn)品基本信息 |
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| 產(chǎn)品編號：F657735 |
| 產(chǎn)品名稱：FMK |
| 產(chǎn)品CAS：821794-92-7 |
| 規(guī)格含量：1mg |
| 產(chǎn)品價格：面議 |
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| 產(chǎn)品詳細介紹 |
| 標準品編號: |
F657735 |
| 名稱: |
FMK |
| 別名: |
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone; FMK-MEA; Fluoromethylketone-MEA |
| CAS號: |
821794-92-7 |
| 分子式: |
C??H??FN?O? |
| 分子量: |
342.37 |
| 種類: |
Standards; Enzyme Activators and Inhibitors; |
| 應用: |
FMK is a potent irreversible RSK1/2 inhibitor (IC50 = 15 nM). Inactivates the C-terminal auto-kinase domain activity. Suppresses RSK2 kinase activity in RSK2-expressing HNSCC cell lines. Reduces HNSCC cell invasive ability. Displays no effect on EGF-stimulated phosphorylation of ERK1 or ERK2. |
| 參考文獻 |
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