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產(chǎn)品基本信息

產(chǎn)品編號(hào)：M219023

產(chǎn)品名稱：(2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylate

產(chǎn)品CAS：

規(guī)格含量：10mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	M219023
名稱:	(2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylate
別名:	(2R,5S)-5-(4-Amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester
參考CAS號(hào):	Unlabelled: 147027-10-9
分子式:	C??¹³CH??N?O?S
分子量:	382.48
種類:	Building Blocks; Isotopic Labeled Analogues;
應(yīng)用:	(2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylate is a labeled analogue of (2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylate (M219020), an intermediate in the synthesis of Lamivudine (L172500), a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.
參考文獻(xiàn)	Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992); Jeong, L., et al.: J. Med. Chem., 36, 181 (1993); Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977)

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