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產(chǎn)品基本信息

產(chǎn)品編號(hào)：P217450

產(chǎn)品名稱：PD-325901

產(chǎn)品CAS：391210-10-9

規(guī)格含量：10mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	P217450
名稱:	PD-325901
別名:	N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide; PD 0325901;PD325901
CAS號(hào):	391210-10-9
分子式:	C??H??F?IN?O?
外觀:	白色至淡黃色固體
熔點(diǎn):	112 - 114°C
分子量:	482.19
儲(chǔ)存:	-20°C Freezer, Under Inert Atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
類別:	Research Tools; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	PD-325901 is the mitogenic extracellular kinase 1/2 (MEK1/2) inhibitor; has potent activity in a no. of cancer cell types in vitro. Selective MEK inhibitor‎.
參考文獻(xiàn)	Davies, H., et al.: Nature, 417, 949 (2002), Wellbrock, C., et al.: Cancer Res., 64, 2338 (2004), Solit, D., et al.: Cancer Res., 67, 11463 (2007), Adjei, A., et al.: J. Clin. Oncol., 26, 2139 (2008),

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