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產(chǎn)品基本信息

產(chǎn)品編號：B692930

產(chǎn)品名稱：tert-Butyl (1R,3R,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate

產(chǎn)品CAS：1564266-54-1

規(guī)格含量：50mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	B692930
名稱:	tert-Butyl (1R,3R,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
別名:	(1R,3R,5R)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic Acid 1,1-Dimethylethyl Ester
CAS號:	1564266-54-1
分子式:	C??H??N?O?
分子量:	226.27
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	tert-Butyl (1R,3R,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate is an intermediate in the synthesis of (2’R,2R,cis)-Saxagliptin (S143475), which is an impurity of Saxagliptin (S143500). Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
參考文獻(xiàn)	Dong, J., et al.: Bioorg. Med. Chem., 22, 1383 (2014); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008)

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