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產(chǎn)品基本信息

產(chǎn)品編號(hào)：C366605

產(chǎn)品名稱：(3S)-4-Chloro-3-hydroxybutyronitrile

產(chǎn)品CAS：127913-44-4

規(guī)格含量：10g

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	C366605
名稱:	(3S)-4-Chloro-3-hydroxybutyronitrile
別名:	(3S)-4-Chloro-3-hydroxybutanenitrile; (S)-4-Chloro-3-hydroxybutanenitrile; (S)-(-)-4-Chloro-3-hydroxybutyronitrile; (S)-4-Chloro-3-hydroxybutyronitrile;
CAS號(hào):	127913-44-4
分子式:	C?H?ClNO
外觀:	Clear Colourless Oil
分子量:	119.55
儲(chǔ)存:	冰箱保存, under inert atmosphere
溶解度:	Chloroform (Sparingly), Methanol (Slightly)
類別:	Building Blocks; Miscellaneous;
應(yīng)用:	(3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
參考文獻(xiàn)	Kanno, O. et al.: Hetero., 53, 173 (2000); Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006); Jiang, C. et al.: Lett. Org. Chem., 9, 520 (2012);

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