產(chǎn)品基本信息
產(chǎn)品編號(hào)：C641510
產(chǎn)品名稱(chēng)：Colistin A Sulfate Hydrate (~90%)
產(chǎn)品CAS：
規(guī)格含量：5mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
C641510
名稱(chēng):
Colistin A Sulfate Hydrate (~90%)
別名:
Polymixin E1; 1,4,7,10,13,16,19-Heptaazacyclotricosane Cyclic peptide deriv. Sulfate; Colistin IV Sulfate Hydrate ; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10→4)-Peptide Sulfate Hydrate ; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10→4)-Peptide Sulfate Hydrate
參考CAS:
Free Base: 7722-44-3
分子式:
C??H???O??N?? •xH?SO? •xH?O
外觀:
白色固體
熔點(diǎn):
>230°C (dec.)
分子量:
1169.46
儲(chǔ)存:
冰箱保存
溶解度:
Water (Slightly)
類(lèi)別:
Standards; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
應(yīng)用:
Colistin A Sulfate Hydrate is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.
參考文獻(xiàn)
Wallace, S. et al.: J. Pharm. Sci., 102, 1578 (2013); Suzuki, T., et al.: J. Biochem., 54, 25 (1963); Barnett, M., et al.: Br. J. Pharmacol. Chemother., 23, 552 (1964); Littlewood, J, M., et al.: Respir. Med., 94, 632 (2000); Li, J., et al.: Int. J. Antimicrob. Ag., 25, 11 (2005); Tsubery, H. et al.: Antimicrob. Agents Chemother., 49, 3122 (2005)
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