產(chǎn)品基本信息
產(chǎn)品編號:D220762
產(chǎn)品名稱:(Decarboxy)-1-Oxo Fexofenadine-d10 Methanol
產(chǎn)品CAS:
規(guī)格含量:10mg
產(chǎn)品價格:面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號:
D220762
名稱:
(Decarboxy)-1-Oxo Fexofenadine-d10 Methanol
別名:
1-(4-(1-Hydroxy-2-methylpropan-2-yl)phenyl)-4-(4-(hydroxydiphenyl-d5-methyl)piperidin-1-yl)butan-1-one;
參考CAS號:
未標(biāo)記:76811-99-9
分子式:
C??H??D??NO?
分子量:
495.72
種類:
Building Blocks; Isotopic Labeled Analogues;
應(yīng)用:
(Decarboxy)-1-Oxo Fexofenadine-d10 Methanol is used in the synthesis of Fexofenadine-d10, the labeled analogue of Fexofenadine (F322470), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.
參考文獻(xiàn)
El Ouarradi, A., et. al.: Tetrahedron, 64, 11738 (2008); Garteiz, D.A., et al.: Arzneim.-Forsch., 32, 1185 (1982); Rampe, D., et al.: Mol. Pharmacol., 44, 1240 (1993); Obradovic, T., et al.: Pharm. Res., 24, 318 (2007)