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產(chǎn)品基本信息

產(chǎn)品編號：D281980

產(chǎn)品名稱：3-Desamino-3,4-dehydro Sitagliptin

產(chǎn)品CAS：1803026-58-5

規(guī)格含量：50mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	D281980
名稱:	3-Desamino-3,4-dehydro Sitagliptin
別名:	(E)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-3-en-1-one
雜質(zhì):	Sitagliptin Tablets EP Impurity FP-C
CAS號:	1803026-58-5
分子式:	C??H??F?N?O
外觀:	白色至白色固體
熔點:	113-115°C
分子量:	390.28
儲存:	-20Â°C Freezer, Under inert atmosphere
溶解性:	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	3-Desamino-3,4-dehydro Sitagliptin is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
參考文獻	Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005); Bergman, A., et al: Clin. Ther. 28, 55 (2006)

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