Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
The labelled analogue of a nuclear receptor retinoid X receptor (RXR) agonist that exerts antiproliferative effects in vascular smooth muscle cells (VSMCs) in vivo and in vitro. A potential therapeutic target for vascular injury and intimal thickening. It efficiently enhanced ABCA1 mRNA expression and apoVIP(LA)I-dependent cellular cholesterol release in differentiated THP-1 cells.
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