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產(chǎn)品基本信息

產(chǎn)品編號：R143007

產(chǎn)品名稱：Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methyl-d3-picolinamide

產(chǎn)品CAS：

規(guī)格含量：10mg

產(chǎn)品價格：面議

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產(chǎn)品詳細介紹

標準品編號:	R143007
名稱:	Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methyl-d3-picolinamide
別名:	4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide
分子式:	C??H??D?ClF?N?O?
分子量:	716.03
類別:	Building Blocks; Isotopic Labeled Analogues;
應(yīng)用:	Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methyl-d3-picolinamide is the labeled analogue of Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methylpicolinamide (R143005), an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
參考文獻	Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)

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