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產品基本信息

產品編號：R535035

產品名稱：Bis(thiazol-5-yl-methyl)[carbonylbis[imino[(2S,3S,5S)-3-hydroxy-1,6-diphenylhexane-5,2-diy

產品CAS：

規(guī)格含量：100mg

產品價格：面議

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產品詳細介紹

標準品編號:	R535035
名稱:	Bis(thiazol-5-yl-methyl)[carbonylbis[imino[(2S,3S,5S)-3-hydroxy-1,6-diphenylhexane-5,2-diyl]]]dicarbamate
雜質:	Ritonavir EP Impurity P
分子式:	C??H??N?O?S?
外觀:	白色至Light Yellow Solid
熔點:	>122°C (dec.)
分子量:	877.08
儲存:	冰箱
溶解度:	DMSO (Sparingly), Methanol (Slightly)
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用:	Ritonavir Impurity P is derived from 2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane (A630525), which is an intermediate in the synthesis of Ritonavir (R535000), a selective HIV protease inhibitor.
參考文獻	Kempf, D., et al.: J. Med. Chem., 41, 602 (1998), Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788(2006)

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