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產(chǎn)品基本信息

產(chǎn)品編號：T310085

產(chǎn)品名稱：1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone

產(chǎn)品CAS：1213781-59-9

規(guī)格含量：25mg

產(chǎn)品價格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	T310085
名稱:	1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone
別名:	N-Acetyl Varenicline; 1-((6R,10S)-9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-yl)ethanone;
CAS號:	1213781-59-9
分子式:	C??H??N?O
分子量:	253.3
類別:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone is related to its parent compound N-Formyl Varenicline (F701650), which is a metabolite of Varenicline and metabolite M5. Also, it is derived from Varenicline Tartrate (V098490), which is a nicotinic α4β2 acetylcholine receptor partial agonist and used to aid in smoking cessation (1,2,3,4).
參考文獻(xiàn)	Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005)

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