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產(chǎn)品基本信息
產(chǎn)品編號(hào)：G797515
產(chǎn)品名稱：GSK2656157
產(chǎn)品CAS：1337532-29-2
規(guī)格含量：50mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
G797515
名稱:
GSK2656157
別名:
1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)-ethanone; 5-[4-Fluoro-1-[(6-methyl-2-pyridinyl)acetyl]-2,3-dihydro-1H-indol-5-yl]-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS號(hào):
1337532-29-2
分子式:
C??H??FN?O
外觀:
白色至淡黃色固體
熔點(diǎn):
194-196°C
分子量:
416.45
儲(chǔ)存:
-20°C Freezer
溶解度:
DMSO (Slightly), Methanol (Slightly)
種類:
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
GSK2656157 is an ATP-competitive and highly selective inhibitor of PKR-like endoplasmic reticulum kinase (PERK) enzyme activity. GSK2656157 also has anti-tumor and anti-angiogenic activity.
參考文獻(xiàn)
Axten, J.M., et al.: ACS Med. Chem. Lett., 4, 964 (2013); Atkins, C., et al.: Cancer Res., 73, 1993 (2013)
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