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產(chǎn)品基本信息

產(chǎn)品編號：M219145

產(chǎn)品名稱：L-Menthyl 2,2-Dihydroxyacetate

產(chǎn)品CAS：111969-64-3

規(guī)格含量：5g

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號:	M219145
名稱:	L-Menthyl 2,2-Dihydroxyacetate
別名:	2,2-Dihydroxyacetic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester; Dihydroxyacetic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester; [1R-(1α,2β,5α)]-Dihydroxyacetic Acid 5-Methyl-2-(1-methylethyl)cyclohexyl Ester; 2,2-Dihydroxyacetic Acid (-)-Menthyl Ester
CAS號:	111969-64-3
分子式:	C??H??O?
外觀:	白色固體
熔點(diǎn):	79-82°C
分子量:	230.3
儲存:	冰箱, under inert atmosphere
溶解度:	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
種類:	Building Blocks; Miscellaneous;
應(yīng)用:	L-Menthyl 2,2-Dihydroxyacetate is used as a reagent in the synthesis of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor used for the treatment of chronic hepatitis B. L-Menthyl 2,2-Dihydroxyacetate is also used as a reagent in the synthesis of 4-acetoxy-3-hydroxyethylazetidin-2-one, a key intermediate for the preparation of penem and carbapenem antibiotics.
參考文獻(xiàn)	Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977); Goodyear, M.D., et al.: Tetrahedron Lett., 46, 8535 (2005); Kametani, T., et al.: Heterocycles, 25, 241 (1987)

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