Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
2-Methyl-3-propylidene-butanedioic Acid 1,4-Dimethyl Ester is an intermediate in the synthesis of 2-Ethyl-3-methylmaleic Anhydride (E923520). 2-Ethyl-3-methylmaleic Anhydride is one of the bioactive ingredients present in essential oil of the leaves of Maytenus obtusifolia (Celastraceae), showed antimicrobial activity against 13 strains of bacteria, and fungus and yeast. The oil showed significant antimicrobial activity against Sthaphylococcus aureus (ATCC 6538), Escherichia coli (ATCC 18739), Listeria monocytogenes (ATCC 9610), Candida albicans (ATCC 13803), Candida tropicalis (LM 37), Candida guilliermondii (LM V70) and Aspergillus flavus (LM 247).
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