產(chǎn)品基本信息
產(chǎn)品編號(hào):P294425
產(chǎn)品名稱:PHA-665752 Hydrate
產(chǎn)品CAS:477575-56-7
規(guī)格含量:100mg
產(chǎn)品價(jià)格:面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
P294425
名稱:
PHVIP(LA)665752 Hydrate
別名:
(3Z)-5-[[(2,6-dichlorophenyl)methyl]sulfonyl]-3-[[3,5-dimethyl-4-[[(2R)-2-(1-pyrrolidinylmethyl)-1-pyrrolidinyl]carbonyl]-1H-pyrrol-2-yl]methylene]-1,3-dihydro-2H-indol-2-one Hydrate; PHA 665752 Hydrate;
CAS號(hào):
477575-56-7
參考CAS號(hào):
477575-56-7-anhydrous
分子式:
C??H??Cl?N?O?S • xH ?O
分子量:
641.61
類別:
Research Tools;
應(yīng)用:
PHVIP(LA)665752 ia a c-Met kinase inhibitor. PHVIP(LA)665752 is ATP-competitive, an active-site inhibitor with greater than 50-fold selectivity for c-Met vs a panel of tyrosine and serine-threonine kinases.
參考文獻(xiàn)
Cheng, H., et al.: J. Clin. Oncol., 20, 1544 (2002), Ma, P., et al.: Cancer Metastasis Rev., 22, 309 (2003), Christensen, J., et al.: Cancer Lett., 225, 1 (2005), Lo Muzio, L., et al.: Tumor Biol., 27, 116 (2006),